In a large skillet over medium heat, brown the ground beef. Add garlic powder, onion powder, salt, pepper, and Worcestershire sauce. Cook until crispy and no longer pink, about 7-10 minutes.

In a medium bowl, combine Greek yogurt, light mayonnaise, ketchup, yellow mustard, and sweet pickle relish. Whisk until smooth and adjust seasoning as desired.

Heat the wraps in the microwave for 10-15 seconds or on a skillet for 30 seconds on each side to make them flexible.

Spread a layer of the sauce on each wrap, add beef filling, lettuce, cheddar cheese, and any optional toppings.

Roll each wrap tightly, tucking in the sides. Toast in a dry skillet over medium heat for 1-2 minutes on each side until golden brown if desired.